Article

A nematode model to evaluate microdeletion phenotype expression

2022-11-09

Abstract excerpt

<h4>ABSTRACT</h4> Microdeletion syndromes are genetic diseases caused by chromosomal deletions too small to be detected by karyotyping. They are typified by complex pleiotropic developmental phenotypes that depend both on the extent of the deletion and variations in genetic background. Microdeletion alleles disrupt several genes simultaneously, often as the result of a single mutagenic event, causing a wide array...

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Literature Corpus work: 9c019e82-e66c-5680-b700-9415092e410c
DOI: 10.1101/2022.11.09.515676

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