Back to search

Article

Forward Genetics Identifies <i>ptr-18</i> and Other Genes as Developmental Regulators of the Four-Cell Tail Tip in <i>C. elegans</i>

2025-08-21

Abstract excerpt

In C. elegans , the epidermis and its overlying extracellular matrix form a primary protective barrier, functioning as the first line of defense against environmental factors. To properly develop those cellular boundaries, a tightly controlled interaction of many molecules and pathways is needed. Mutant alleles of paqr-2 and iglr-2 (lipid homeostasis), dpy-21 (membrane trafficking), and sma-1 (actin-binding s...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
a966a599-8dde-54c3-90ad-c2a78ede1d22
DOI
10.1101/2025.08.20.671392
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Forward Genetics Identifies <i>ptr-18</i> and Other Genes as Developmental Regulators of the Four-Cell Tail Tip in <i>C. elegans</i>DOI 10.1101/2025.08.20.671392
Forward genetics identifies cuticle and regulatory genes underlying cellular boundary integrity in C. elegans.Semantic proximity
TAT-1, a phosphatidylserine flippase, affects molting and regulates membrane trafficking in the epidermis of <i>C. elegans</i>Semantic proximity
A complete collagen IV fluorophore knock-in toolkit reveals α-chain diversity in basement membraneSemantic proximity
A collagen IV fluorophore knock-in toolkit reveals trimer diversity in C. elegans basement membranes.Semantic proximity
Structural and physiological functions of Caenorhabditis elegans epidermisSemantic proximity
CRISPR-Cas9 human gene replacement and phenomic characterization in <i>Caenorhabditis elegans</i> to understand the functional conservation of human genes and decipher variants of uncertain significanceSemantic proximity
A nematode model to evaluate microdeletion phenotype expressionSemantic proximity
Mutation in F-actin Polymerization Factor Suppresses Distal Arthrogryposis Type 5 (DA5) PIEZO2 Pathogenic Variant in <i>Caenorhabditis elegans</i>Semantic proximity
MLT-11 is necessary for <i>C. elegans</i> embryogenesis and conserved sequences play distinct roles in cuticle structureSemantic proximity
Multiscale characterization of <i>Caenorhabditis elegans</i> mutants to probe functional mechanisms of human actin pathological variantsSemantic proximity
A <i>pcyt-1</i> Allelic Series Reveals In Vivo Consequences of Reduced Phosphatidylcholine Synthesis in <i>C. elegans</i>Semantic proximity
<i>Caenorhabditis elegans</i> germline development requires <i>brap-2</i>Semantic proximity
Select a neighboring publication to make it the new centre.