Article

Genome Editing in <i>Caenorhabditis briggsae</i> using the CRISPR/Cas9 System

2015-06-18

Abstract excerpt

<h4>Author Summary</h4> The CRISPR/Cas9 system has recently emerged as a powerful tool to engineer the genome of an organism. The system is adopted from bacteria where it confers immunity against invading foreign DNA. This work reports the first successful use of the CRISPR/Cas9 system in C. briggsae , a cousin of the well-known nematode C. elegans . We used two plasmids, one expressing Cas9 endonuclease and th...

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Literature Corpus work: 3df3d195-a4e2-555f-a995-26841b6ab7b7
DOI: 10.1101/021121

Open publication

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