Article

Assessing the role of rare pathogenic variants in heart failure progression by exome sequencing in 8,089 patients

2023-08-05

Abstract excerpt

Most therapeutic development is targeted at slowing disease progression, often long after the initiating events of disease incidence. Heart failure is a chronic, life-threatening disease and the most common reason for hospital admission in people over 65 years of age. Genetic factors that influence heart failure progression have not yet been identified. We performed an exome-wide association study in 8,089 patient...

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Literature Corpus work: 9be046a7-be69-5d9a-bb17-ef4da4e4f263
DOI: 10.1101/2023.07.28.23293350

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