Article

Unraveling the Genetic Drivers of Heart Failure from Cardiac Endothelial Cells via Single-Cell RNA-Sequencing Data and Machine Learning Model

2023-05-08

Abstract excerpt

<h4>Background: </h4> Heart failure is a complex syndrome that hinders the heart's ability to provide oxygen to the tissues and is a significant cause of death globally. Given that left ventricular failure is more common than left atrial failure, this study utilizes single-cell RNA-sequencing data to detect differentially expressed genes (DEGs) between the endothelial cells of the two chambers and examines whether...

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Literature Corpus work: a7f73a50-5862-5af6-be7f-5837009c36e5
DOI: 10.21203/rs.3.rs-2875387/v1

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