Article

Genome-wide association and Mendelian randomisation analysis provide insights into the pathogenesis of heart failure

2019-07-08

Abstract excerpt

Abstract: Heart failure (HF) is a leading cause of morbidity and mortality worldwide. A small proportion of HF cases are attributable to monogenic cardiomyopathies and existing genome-wide association studies (GWAS) have yielded only limited insights, leaving the observed heritability of HF largely unexplained. We report results from a GWAS meta-analysis of HF comprising 47,309 cases and 930,014 controls. Twelve i...

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Literature Corpus work: 9172cd5c-fe9b-590a-b941-bfc8fda107ed
DOI: 10.17863/cam.48498

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