Cut homeodomain transcription factor is a novel regulator of cortex glia morphogenesis and maintenance of neural niche

Abstract excerpt

Cortex glia in Drosophila central nervous system forms a niche around neural cells for necessary signals to establish cross-talk with their surroundings. These cells grow and expand their thin processes around neural cell bodies. Although essential for the development and function of the nervous system, how these cells make extensive and intricate connected networks remain largely unknown. Here we show that Cut,...

Topics

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• Basic Helix-Loop-Helix Transcription Factors
• Body Patterning
• Cyclin-Dependent Kinase Inhibitor p27
• Epigenetics and DNA Methylation
• Interneurons
• Mesenchymal stem cell research
• Models, Neurological
• Neurogenesis and neuroplasticity mechanisms

Identifiers and source

Literature Corpus work

9bc8164f-c9d7-577d-a212-e5fa73685988

DOI

10.1101/2022.10.31.514621