Article

Progenitor Diversity and Architecture of the Human Ganglionic Eminences Shaping the Basal Ganglia

2026-01-02

Abstract excerpt

The embryonic medial and lateral ganglionic eminences (MGE, LGE) are the principal sources of most neurons and glia for the basal ganglia. In primates, the MGE has a distinctive cytoarchitecture characterized by doublecortin enriched cellular nests (DENs), yet the architectonic organization underlying DEN formation, the molecular heterogeneity of ganglionic eminence progenitors and their lineage relationships, rem...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 766e1c9e-977e-58eb-9c12-40474752d20a
DOI: 10.64898/2025.12.31.697063

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Progenitor Diversity and Architecture of the Human Ganglionic Eminences Shaping the Basal GangliaDOI 10.64898/2025.12.31.697063Read

Human basal radial glia morphotypes are transcriptionally distinct and exhibit different cell fate determinationSemantic proximity Read

Multiscale Spatial Transcriptomic Atlas of Human Basal Ganglia Cell-Type and Cellular Community OrganizationSemantic proximity Read

Cortical arealization of interneurons defines shared and distinct molecular programs in developing human and macaque brainsSemantic proximity Read

A cross-species spatial transcriptomic atlas of the human and non-human primate basal gangliaSemantic proximity Read

Co-development of central and peripheral neurons with trunk mesendoderm in human elongating multi-lineage organized gastruloids.Semantic proximity Read

Cross-species consensus atlas of the primate basal gangliaSemantic proximity Read

Integrative genomic analysis of early neurogenesis reveals a temporal genetic program for differentiation and specification of preplate and Cajal-Retzius neuronsSemantic proximity Read

A Multimodal Single-Cell Epigenomic and 3D Genome Atlas of the Human Basal GangliaSemantic proximity Read

A Single-Cell and Spatial 3D Multi-omic Atlas of Developing Human Basal Ganglia and Inhibitory NeuronsSemantic proximity Read

Compartments in medulloblastoma with extensive nodularity are connected through differentiation along the granular precursor lineageSemantic proximity Read

The caudal ganglionic eminence is a source of distinct cortical and subcortical cell populations.Semantic proximity Read

Circuit specific specialization of human basal ganglia astrocytesSemantic proximity Read