Article

<i>Drosophila ClC-a</i> is required in glia of the stem cell niche for proper neurogenic proliferation and wiring of neural circuits

2018-11-29

Abstract excerpt

<h4>ABSTRACT</h4> Glial cells form part of the neural stem cell niche and express a wide variety of ion channels; however, the contribution of these channels to nervous system development is poorly understood. We explored the function of the Drosophila ClC-a chloride channel, since its mammalian ortholog CLCN2 is expressed in glial cells, and defective channel function results in leukodystrophies, which in huma...

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Literature Corpus work: 76ce7de2-363b-57ff-84f0-14582448b102
DOI: 10.1101/482778

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