Article

Transcriptional and synaptic regulation of NMDA glutamate receptor-mediated hippocampal plasticity and memory

2025-01-19

Abstract excerpt

<h4>SUMMARY</h4> Synapse-to-nucleus signaling regulates activity-dependent synaptic plasticity underlying memory by linking N-methyl-D-aspartate (NMDA) glutamate receptors (GluN) to gene transcription mediated by the transcription factor cAMP-response element binding protein (CREB), but the underlying gene programs mediating potentiation at excitatory synapses are unknown. Here, we analyzed genome-wide chromatin...

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Literature Corpus work: 9bc0a080-5188-58ec-b633-ad710bdee0ab
DOI: 10.1101/2025.01.19.633774

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