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Article

GABA-cAMP response element-binding protein signaling regulates maturation and survival of newly generated neurons in the adult hippocampus.

The Journal of neuroscience : the official journal of the Society for Neuroscience - 24 Jun 2009

Jagasia Ravi, Steib Kathrin, Englberger Elisabeth, Herold Sabine, Faus-Kessler Theresa, Saxe Michael, Gage Fred H, Song Hongjun, Lie D Chichung

Abstract excerpt

Survival and integration of new neurons in the hippocampal circuit are rate-limiting steps in adult hippocampal neurogenesis. Neuronal network activity is a major regulator of these processes, yet little is known about the respective downstream signaling pathways. Here, we investigate the role of cAMP response element-binding protein (CREB) signaling in adult hippocampal neurogenesis. CREB is activated in new...

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Identifiers

PMID: 19553437
DOI: 10.1523/JNEUROSCI.1054-09.2009
PMCID: PMC2776747

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DCX

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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