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SequenceCraft: Machine learning-based resource for exploratory analysis of RNA-cleaving deoxyribozymes

2024-08-19

Abstract excerpt

<title>Abstract</title> <p>Deoxyribozymes or DNAzymes represent artificial short DNA sequences bearing many catalytic properties. In particular, DNAzymes able to cleave RNA sequences have a huge potential in gene therapy and sequence-specific analytic detection of disease markers. This activity is provided by catalytic cores able to perform site-specific hydrolysis of the phosphodiester bond of an RNA substrate....

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Literature Corpus work: 9b8b002d-5521-5e24-ace0-393a03f2cdd1
DOI: 10.21203/rs.3.rs-4777734/v1

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