Article
TREM2 Risk Variants with Alzheimer’s Disease Differ in Rate of Cognitive Decline
2024-11-08
Abstract excerpt
<title>Abstract</title> <p>Rare variants of the triggering receptor expressed on myeloid cell 2 (<italic>TREM2</italic>) gene are major risk factors for Alzheimer’s disease (AD), and drugs targeting the TREM2 protein are being developed. However, it is unknown whether carriers of a <italic>TREM2</italic> risk variant have a clinically distinct AD phenotype. Here we studied a full range of clinical measures in a l...
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Identifiers and source
- Literature Corpus work
- 9b7d08d5-c77b-5b86-ade6-8173a5ba1b76
- DOI
- 10.21203/rs.3.rs-5310076/v1