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<i>TREM2</i>Risk Variants with Alzheimer’s Disease Differ in Rate of Cognitive Decline

2024-10-18

Abstract excerpt

<h4>ABSTRACT</h4> Rare variants of the triggering receptor expressed on myeloid cell 2 ( TREM2 ) gene are major risk factors for Alzheimer’s disease (AD), and drugs targeting the TREM2 protein are being developed. However, it is unknown whether carriers of a TREM2 risk variant have a clinically distinct AD phenotype. Here we studied a full range of clinical measures in a large cohort of TREM2 variant carriers ( n...

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Literature Corpus work
41cbe705-c752-5f19-bab4-8c91a45e5a6f
DOI
10.1101/2024.10.17.24315643
Open publication

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<i>TREM2</i>Risk Variants with Alzheimer’s Disease Differ in Rate of Cognitive DeclineDOI 10.1101/2024.10.17.24315643
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