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Genetically-proxied impaired GIPR signalling and risk of 6 cancers

2022-08-07

Abstract excerpt

<h4>Background</h4> Preclinical and human genetics studies suggest that impaired glucose-dependent insulinotropic polypeptide receptor (GIPR) signalling worsens glycaemic control. The relationship between GIPR signalling and risk of cancers influenced by impaired glucose homeostasis is unclear. <h4>Methods</h4> We examined the association of a missense variant in GIPR , rs1800437 (E354Q), shown to impair long-t...

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Literature Corpus work
9b396d30-a5e6-51d8-8a16-53c4900ed6d4
DOI
10.1101/2022.08.06.22278459
Open publication

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Genetically-proxied impaired GIPR signalling and risk of 6 cancersDOI 10.1101/2022.08.06.22278459
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