Article

<i>Fgf4</i> is critical for maintaining <i>Hes7</i> levels and Notch oscillations in the somite segmentation clock

2020-02-12

Abstract excerpt

During vertebrate development, the presomitic mesoderm (PSM) is periodically segmented into somites, which will form the segmented vertebral column and associated muscle, connective tissue, and dermis. The periodicity of somitogenesis is regulated by a segmentation clock of oscillating Notch activity. Here, we examined mouse mutants lacking only Fgf4 or Fgf8 , which we previously demonstrated act redundantly to...

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Literature Corpus work: 9ad0f9e8-f8c0-5e64-ab6f-1025bd9d763b
DOI: 10.1101/2020.02.12.945931

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