Article
Involvement of SIP1 in positioning of somite boundaries in the mouse embryo.
Developmental dynamics : an official publication of the American Association of Anatomists - 1 Oct 2005
Maruhashi Mitsuji, Van De Putte Tom, Huylebroeck Danny, Kondoh Hisato, Higashi Yujiro
Abstract excerpt
Periodical production of somites provides an excellent model system for understanding genesis of metameric structures underlying embryonic development. This study reports production of somites with roughly half rostro-caudal length in homozygous Sip1 (Smad-interacting protein 1) knockout mouse embryos. This altered periodicity of somitogenesis is caused by the rostral expansion of the expression domain of genes...
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