Article

A Chemical Epigenetic Probe to Capture the Site-Specific DNA-Binding Protein Complex

2025-03-11

Abstract excerpt

<title>Abstract</title> <p>Site-specific DNA binding by proteins is critical for regulating genetic activity and cell fate decision. However, identifying proteins bound to specific genomic regions (e.g., promoter or enhancer) remains challenging. To address this, we developed a chemical epigenetic tool, named Site-specific non-canonical amino acid resolved Protein EnRichment (SUPER) system, incorporating a photo-...

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Literature Corpus work: 9ac36c7f-c175-52ad-ac91-b4c9b3ccc688
DOI: 10.21203/rs.3.rs-5915426/v1

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