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Targeted DamID detects cell-type specific histone modifications <i>in vivo</i>

2024-04-11

Abstract excerpt

Histone modifications play a key role in regulating gene expression and cell fate during development and disease. Current methods for cell-type specific genome-wide profiling of histone modifications require dissociation and isolation of cells and are not compatible with all tissue types. Here we adapt Targeted DamID to recognise specific histone marks, by fusing chromatin binding proteins or single-chain antibodi...

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Identifiers and source

Literature Corpus work
31857070-32a5-558e-a807-5d71ba39991e
DOI
10.1101/2024.04.11.589050
Open publication

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Targeted DamID detects cell-type specific histone modifications <i>in vivo</i>DOI 10.1101/2024.04.11.589050
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