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Long-range single-molecule mapping of chromatin modification in eukaryotes

2021-07-09

Abstract excerpt

The epigenetic modifications of histones are essential markers related to the development and pathogenesis of diseases, including human cancers. Mapping histone modification has emerged as the widely used tool for studying epigenetic regulation. However, existing approaches are limited by fragmentation and short-read sequencing represent the average chromatin status in samples and cannot provide information about...

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Literature Corpus work
3a1b85aa-5ba4-5343-8eed-cc9894afac89
DOI
10.1101/2021.07.08.451578
Open publication

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Long-range single-molecule mapping of chromatin modification in eukaryotesDOI 10.1101/2021.07.08.451578
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