Article

Affinity proteomic dissection of the human nuclear cap-binding complex interactome

2020-04-21

Abstract excerpt

<h4>ABSTRACT</h4> A 5’, 7-methylguanosine cap is a quintessential feature of RNA polymerase II-transcribed RNAs, and a textbook aspect of co-transcriptional RNA processing. The cap is bound by the cap-binding complex (CBC), canonically consisting of nuclear cap-binding proteins 1 and 2 (NCBP1/2). The CBC has come under renewed investigative interest in recent years due to its participation in RNA-fate decisions v...

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Literature Corpus work: 035f214b-3d77-569d-be5d-4582a90b908f
DOI: 10.1101/2020.04.20.048470

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