Article

High through-put identification of miR-145 targets in human articular chondrocytes

2020-02-03

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Objective</h4> MicroRNAs play a key role in biological processes, including cartilage development and homeostasis and are dysregulated in many diseases, including osteoarthritis. MiR-145 modulation induces profound changes in the human articular chondrocyte (HAC) phenotype, partially through direct repression of SOX9 . Since miRNAs can simultaneously silence multiple targets, we aimed to i...

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Literature Corpus work: 9a70ade3-3e18-5578-859f-5080c8d814c3
DOI: 10.1101/2020.02.03.931683

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