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Article

MicroRNA‐140 is expressed in differentiated human articular chondrocytes and modulates interleukin‐1 responses

27 Aug 2009

Abstract excerpt

OBJECTIVE: MicroRNA (miRNA) are a class of noncoding small RNAs that act as negative regulators of gene expression. MiRNA exhibit tissue-specific expression patterns, and changes in their expression may contribute to pathogenesis. The objectives of this study were to identify miRNA expressed in articular chondrocytes, to determine changes in osteoarthritic (OA) cartilage, and to address the function of miRNA-140...

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PMID: 19714579
DOI: 10.1002/art.24745

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