Long noncoding RNA DANCR regulates miR-1305 -Smad 4 axis to promote chondrogenic differentiation of human synovium-derived mesenchymal stem cells

Abstract excerpt

miRNAs have been reported to regulate cellular differentiation by modulating multiple signaling pathways. Long noncoding RNA (lnc RNA) DANCR was previously identified to be critical for the chondrogenesis of human synovium-derived mesenchymal stem cells (SMSC), however, the underlying molecular mechanism requires better understanding. Here, miRNA expression profiling in DANCR overexpressed in SMSCs identified...

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