Article
miR-1247 functions by targeting cartilage transcription factor SOX9.
The Journal of biological chemistry - 25 Oct 2013
Martinez-Sanchez Aida, Murphy Chris L
Abstract excerpt
microRNAs are a large and essential class of gene regulators that play key roles in development, homeostasis, and disease. They are necessary for normal skeletal development, and their expression is altered in arthritis. However, the specific role of individual microRNAs is only beginning to be unraveled. Using microRNA expression profiling in healthy human articular cartilage cells (chondrocytes), we identified...
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