c-MYC–miRNA circuitry

doi:10.4161/cc.27646

Article

c-MYC–miRNA circuitry

6 Jan 2014

Abstract excerpt

MYC (c-Myc) deregulation has been frequently associated with aggressive lymphomas and adverse clinical outcome in B-cell malignancies. MYC has been implicated in controlling the expression of miRNAs, and MYC-regulated miRNAs affect virtually all aspects of the hallmarks of MYC-driven lymphomas. Increasing evidence has indicated that there is significant cross-talk between MYC and miRNAs, with MYC regulating...

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