Article

Myc-dependent cell competition and proliferative response requires induction of the ribosome biogenesis regulator Peter Pan

2020-05-06

Abstract excerpt

The transcription factor Myc is activated in most major forms of human cancer. Myc regulates a large set of target genes, and drives cell growth across animal phyla. However, it has not been clear which target genes are required for Myc-induced growth, and whether the targets are individually necessary or act in an additive fashion. Here, we have used comparative functional genomics to identify a core set of Myc t...

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Literature Corpus work: 8c0c6153-0cd4-553d-aa83-98b4caf3072e
DOI: 10.1101/2020.05.06.080283

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