Article
MYC/MAX balance dictates cell progenitor fate by altering the HOX program in the <i>Drosophila</i> eye
2025-12-15
Abstract excerpt
The transcription factor MYC acts canonically as heterodimer with MAX to promote growth, proliferation, and metabolic adaptation. Although MYC and MAX relative levels are normally kept in balance under physiological conditions, those levels are often dysregulated in many human cancers where MYC is overexpressed and MAX can sometimes be reduced. How altered stoichiometry of MYC/MAX can impact on cell biology is not...
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Identifiers and source
- Literature Corpus work
- 201c4b7e-ea92-56a7-8dcb-92bd4b57cd23
- DOI
- 10.64898/2025.12.12.693907