Article
Computational Characterization of Suppressive Immune Microenvironments in Glioblastoma.
Cancer research - 1 Oct 2018
Luoto Suvi, Hermelo Ismaïl, Vuorinen Elisa M, Hannus Paavo, Kesseli Juha, Nykter Matti, Granberg Kirsi J
Abstract excerpt
The immunosuppressive microenvironment in glioblastoma (GBM) prevents an efficient antitumoral immune response and enables tumor formation and growth. Although an understanding of the nature of immunosuppression is still largely lacking, it is important for successful cancer treatment through immune system modulation. To gain insight into immunosuppression in GBM, we performed a computational analysis to model...
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