Article

Crosstalk between lymphoid and myeloid cells orchestrates glioblastoma immunity through Interleukin 10 signaling

2021-02-17

Abstract excerpt

<title>Abstract</title> <p>Despite recent advances in cancer immunotherapy, its efficacy in Glioblastoma (GBM) is limited due to poor understanding of molecular states and cellular plasticity of immune cells within the tumor microenvironment. Here, we combined spatial and single-cell transcriptomics of 47.284 immune cells, to map the potential cellular interactions leading to the immunosuppressive microenvironmen...

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Literature Corpus work: 12449cd3-8779-535c-ae12-526b88ccc523
DOI: 10.21203/rs.3.rs-244157/v1

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