Article

MTM: a multi-task learning framework to predict individualized tissue gene expression profiles

2022-10-21

Abstract excerpt

Predicting tissue expression profiles from peripheral ‘surrogate’ samples, especially blood transcriptome, has become an effective alternative when invasive procedures are not ideal. However, existing approaches ignore tissue-shared intrinsic relevance, inevitably limiting predictive performance. Here, we propose a unified deep learning-based multi-task learning framework, Multi-tissue Transcriptome Mapping (MTM),...

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Literature Corpus work: 99f5532b-2e88-5cf2-bf32-81231a933421
DOI: 10.1101/2022.10.19.512838

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