Article
AGEP_TWAS: A Deep Learning-Based Framework for Predicting Gene Expression Levels in Tissues.
IEEE transactions on computational biology and bioinformatics - 1 Jan 2026
Wang Sizhe, Zhou Zhichao, Li Chen, Cai Yudong, Wang Jiong, Zhang Zhuangbiao, Li Ran, Niyazbekova Zhannur, Jiang Yu, Liu Quanzhong
Abstract excerpt
Accurate prediction of gene expression levels across different tissues is of great significance in understanding the functional roles of genes in various biological processes and assisting in transcriptome-wide association studies (TWAS). Traditional methods rely on the construction of a prediction model for each gene in a specific tissue, which is time-consuming and inefficient when dealing with numerous genes...
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