Article

β-RA targets mitochondrial metabolism and adipogenesis, leading to therapeutic benefits against CoQ deficiency and age-related overweight

2021-04-14

Abstract excerpt

Primary mitochondrial diseases are caused by mutations in mitochondrial or nuclear genes, leading to abnormal function of specific mitochondrial pathways. Mitochondrial dysfunction is also a secondary event in more common pathophysiological conditions, such as obesity and metabolic syndrome. In both cases, the improvement and management of mitochondrial homeostasis remains challenging. Here, we show that beta-reso...

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Literature Corpus work: 995f1457-28eb-59d7-be5c-4be5ae36a23f
DOI: 10.1101/2021.04.13.438670

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