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Article

Coenzyme Q biosynthesis in health and disease.

Biochimica et biophysica acta - 1 Aug 2016

Acosta Manuel Jesús, Vazquez Fonseca Luis, Desbats Maria Andrea, Cerqua Cristina, Zordan Roberta, Trevisson Eva, Salviati Leonardo

Abstract excerpt

Coenzyme Q (CoQ, or ubiquinone) is a remarkable lipid that plays an essential role in mitochondria as an electron shuttle between complexes I and II of the respiratory chain, and complex III. It is also a cofactor of other dehydrogenases, a modulator of the permeability transition pore and an essential antioxidant. CoQ is synthesized in mitochondria by a set of at least 12 proteins that form a multiprotein...

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PMID: 27060254
DOI: 10.1016/j.bbabio.2016.03.036

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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