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Article

The molecular genetics of coenzyme Q biosynthesis in health and disease.

Biochimie - 1 May 2014

Laredj Leila N, Licitra Floriana, Puccio Hélène M

Abstract excerpt

Coenzyme Q, or ubiquinone, is an endogenously synthesized lipid-soluble antioxidant that plays a major role in the mitochondrial respiratory chain. Although extensively studied for decades, recent data on coenzyme Q have painted an exciting albeit incomplete picture of the multiple facets of this molecule's function. In humans, mutations in the genes involved in the biosynthesis of coenzyme Q lead to a...

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Identifiers

PMID: 24355204
DOI: 10.1016/j.biochi.2013.12.006

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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