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Primary and secondary coenzyme Q10 deficiency: the role of therapeutic supplementation.

Nutrition reviews - 1 Mar 2013

Potgieter Marnie, Pretorius Etheresia, Pepper Michael S

Abstract excerpt

Coenzyme Q10 (CoQ10) is the only lipid-soluble antioxidant that animal cells synthesize de novo. It is found in cell membranes and is particularly well known for its role in the electron transport chain in mitochondrial membranes during aerobic cellular respiration. A deficiency in either its bioavailability or its biosynthesis can lead to one of several disease states. Primary deficiency has been well described...

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PMID: 23452285
DOI: 10.1111/nure.12011

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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