Article

A2A adenosine receptor agonist reduced MMP8 expression in healthy M2-like macrophages but not in macrophages from ankylosing spondylitis patients

2022-05-18

Abstract excerpt

<h4>Background: </h4> Ankylosing spondylitis (AS) is an inflammatory autoimmune disease that mostly affects different joints of the body. Macrophages are the predominant cells that mediate disease progression by secreting several pro-inflammatory mediators. Different receptors are involved in macrophages' function including the adenosine receptors (AR). We wanted to assess the effect of applying A 2A adenosine rec...

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Literature Corpus work: 98e3c130-6dea-5fe1-84a8-59dc057083d6
DOI: 10.21203/rs.3.rs-1641431/v1

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