MMP-8 single-nucleotide polymorphisms are related to ankylosing spondylitis in Chinese Han population.

doi:10.1097/MD.0000000000012136

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MMP-8 single-nucleotide polymorphisms are related to ankylosing spondylitis in Chinese Han population.

Medicine - 1 Aug 2018

Meng Chenyang, Bai Rui, Zhao Zhenqun, Huang Guimei, Jin Tianbo, Feng Wei, Liu Wanlin

Abstract excerpt

Ankylosing spondylitis (AS) is an extreme form of inflammatory arthritis which always leads to bony fusion of vertebral and chronic pain of back. A lot of genes including interleukin, matrix metalloproteinases (MMPs), and endoplasmic reticulum aminopeptidase were found associated with AS. MMP family members were involved in the autoimmune disease and orthopedic diseases such as rheumatoid arthritis and...

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PMID: 30170451
DOI: 10.1097/MD.0000000000012136
PMCID: PMC6392754

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