Gene expression analysis of macrophages derived from ankylosing spondylitis patients reveals interferon‐γ dysregulation

Abstract excerpt

OBJECTIVE: To determine whether macrophages, a type of cell implicated in the pathogenesis of ankylosing spondylitis (AS), exhibit a characteristic gene expression pattern. METHODS: Macrophages were derived from the peripheral blood of 8 AS patients (median disease duration 13 years [range <1-43 years]) and 9 healthy control subjects over 7 days with the use of granulocyte-macrophage colony-stimulating factor....

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Macrophage Migration Inhibitory Factor
• Share to Rheumatoid Arthritis Research and Therapies
• Share to Spondyloarthritis Studies and Treatments