Article

Using lifestyle information in polygenic modeling of blood pressure traits: a simple method to reduce bias

2024-06-08

Abstract excerpt

Complex traits are determined by the effects of multiple genetic variants, multiple environmental factors, and potentially their interaction. Predicting complex trait phenotypes from genotypes is a fundamental task in quantitative genetics that was pioneered in agricultural breeding for selection purposes. However, it has recently become important in human genetics. While prediction accuracy for some human complex...

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Literature Corpus work: 98a8754e-f8b3-59e7-a534-e16a21dd67a9
DOI: 10.1101/2024.06.05.597631

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