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Article

Genetic Predisposition to High Blood Pressure and Lifestyle Factors: Associations With Midlife Blood Pressure Levels and Cardiovascular Events.

Circulation - 13 Feb 2018

Pazoki Raha, Dehghan Abbas, Evangelou Evangelos, Warren Helen, Gao He, Caulfield Mark, Elliott Paul, Tzoulaki Ioanna

Abstract excerpt

BACKGROUND: High blood pressure (BP) is a major risk factor for cardiovascular diseases (CVDs), the leading cause of mortality worldwide. Both heritable and lifestyle risk factors contribute to elevated BP levels. We aimed to investigate the extent to which lifestyle factors could offset the effect of an adverse BP genetic profile and its effect on CVD risk. METHODS: We constructed a genetic risk score for high...

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Identifiers

PMID: 29254930
DOI: 10.1161/CIRCULATIONAHA.117.030898

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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