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Sex effects on gene expression across the human cerebral cortex at single cell resolution

2025-07-04

Abstract excerpt

Sex differences in brain-related health outcomes may be a consequence of differences in gene expression. However, most current knowledge relies on studies of bulk tissue or isolated brain regions. Here, we present a large-scale single-cell analysis of transcriptomic sex differences in the human brain, using 169 samples from 15 females and 15 males across six cortical regions, selected based on in vivo neuroimaging...

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Identifiers and source

Literature Corpus work
5a72b8e2-4e40-5732-bd35-d0a01b45bb08
DOI
10.1101/2025.06.30.661781
Open publication

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Sex effects on gene expression across the human cerebral cortex at single cell resolutionDOI 10.1101/2025.06.30.661781
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