Article
A Higher Dysregulation Burden of Brain DNA Methylation in Female Patients Implicated in the Sex Bias of Schizophrenia
2023-01-30
Abstract excerpt
<title>Abstract</title> <p>Sex differences are pervasive in schizophrenia (SCZ), but the extent and magnitude of DNA methylation (DNAm) changes underlying these differences remain uncharacterized. In this study, sex-stratified differential DNAm analysis was performed in postmortem brain samples from 117 SCZ and 137 controls, partitioned into discovery and replication datasets. Three differentially methylated posi...
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Identifiers and source
- Literature Corpus work
- 90397e63-f74a-51f9-bafe-e4153929c249
- DOI
- 10.21203/rs.3.rs-2496133/v1