Article

Exploiting Cancer Dormancy Signaling Mechanisms in Epithelial Ovarian Cancer Through Spheroid and Organoid Analysis

2024-12-20

Abstract excerpt

Epithelial ovarian cancer (EOC) exhibits a unique mode of metastasis, involving spheroid formation in the peritoneum. Our research on EOC spheroid cell biology has provided valuable insights into the signalling plasticity associated with metastasis. We speculate that EOC cells modify their biology between tumor and spheroid states during cancer dormancy, although the specific mechanisms underlying this transition...

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Literature Corpus work: 985e63c7-d7a0-5215-bac3-4af754a6a8c5
DOI: 10.20944/preprints202412.1726.v1

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