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A cell cycle centric view of tumour dormancy

22 Aug 2023

Abstract excerpt

Tumour dormancy and recurrent metastatic cancer remain the greatest clinical challenge for cancer patients. Dormant tumour cells can evade treatment and detection, while retaining proliferative potential, often for years, before relapsing to tumour outgrowth. Cellular quiescence is one mechanism that promotes and maintains tumour dormancy due to its central role in reducing proliferation, elevating...

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PMID: 37608096
DOI: 10.1038/s41416-023-02401-z

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