Article

A CDCA2 - MYC positive feedback loop controls cancer cells survival

2025-02-28

Abstract excerpt

MYC transcription factors are encoded by a small family of genes which include, in addition to the prototype member MYC , MYCN and MYCL . The majority of human cancers display expression alterations of MYC genes and their products, making this group of oncoproteins among the most relevant therapeutic targets in oncology. MYC is regulated at multiple levels, and protein phosphorylation is a critical mechanism u...

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Literature Corpus work: 985091d1-3c10-549a-adb2-0f411607017d
DOI: 10.1101/2025.02.28.640789

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