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Article

When protein destruction runs amok, malignancy is on the loose.

Cancer cell - 1 Oct 2003

Pagano Michele, Benmaamar Ramla

Abstract excerpt

Ubiquitin-dependent proteolysis ensures that specific protein functions are turned off at the right time, in the right place, and in a unidirectional fashion. The high substrate specificity of the system is determined by a large family of ubiquitin ligases, which competes with the protein kinases...

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Identifiers

PMID: 14585352
DOI: 10.1016/s1535-6108(03)00243-5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-14585352-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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