MTBP and MYC: A Dynamic Duo in Proliferation, Cancer, and Aging

doi:10.3390/biology11060881

Article

MTBP and MYC: A Dynamic Duo in Proliferation, Cancer, and Aging

8 Jun 2022

Abstract excerpt

The oncogenic transcription factor c-MYC (MYC) is highly conserved across species and is frequently overexpressed or dysregulated in human cancers. MYC regulates a wide range of critical cellular and oncogenic activities including proliferation, metabolism, metastasis, apoptosis, and differentiation by transcriptionally activating or repressing the expression of a large number of genes. This activity of MYC is...

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