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CRISPR-CISH: An <i>in situ</i> chromogenic DNA repeat detection system for research and life science education

2025-02-22

Abstract excerpt

In situ hybridization is a technique to visualize specific DNA sequences within nuclei and chromosomes. Various DNA in situ fluorescent labeling methods have been developed, which typically involve global DNA denaturation prior to the probe hybridization and often require fluorescence microscopes for visualization. Here, we report the development of a CRISPR/dCas9-mediated chromogenic in situ DNA detection (CRIS...

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Literature Corpus work
980ab851-de89-5605-aa12-2f32e5aeafe1
DOI
10.1101/2025.02.20.639243
Open publication

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CRISPR-CISH: An <i>in situ</i> chromogenic DNA repeat detection system for research and life science educationDOI 10.1101/2025.02.20.639243
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