Article

Continuous single cell transcriptome dynamics reveal a default vascular smooth muscle fate of FLK1 mesoderm

2018-07-23

Abstract excerpt

Blood and endothelial cells arise from hemangiogenic progenitors that are specified from FLK1-expressing mesoderm by the transcription factor ETV2. FLK1 mesoderm also contributes to other tissues, including vascular smooth muscle (VSM) and cardiomyocytes. However, the developmental process of FLK1 mesoderm generation and its allocation to various cell fates remain obscure. Recent single cell RNA-sequencing (scRNA-...

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Literature Corpus work: 97372349-67d8-505d-a70e-0a9c6c2736f1
DOI: 10.1101/374629

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